4.1 Article Proceedings Paper

Obese and Nonobese Recipients Had Similar Need for Ventilatory Support After Liver Transplantation

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TRANSPLANTATION PROCEEDINGS
卷 43, 期 1, 页码 165-169

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.transproceed.2010.12.004

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Background. Obesity is a risk factor for patients undergoing major surgery. In liver transplantation, the morbidity and mortality in these patients may be higher owing to concomitant diseases that may prolong hospital stay. Moreover, the restrictive respiratory pattern in these patients, associated with pulmonary complications related to liver disease can impact the postoperative recovery. We sought to analyze the impact of high body mass index (BMI) on hospital and intensive care unit (ICU) stay, necessity and length of use either invasive and noninvasive ventilatory support in the early postoperative period after liver transplantation. Patients and Methods. Between January 2007 and March 2009, we performed 85 liver transplantations in adult patients. BMI was calculated on the day of the transplantation. Data from 136 recipients undergoing OLT were reviewed by age, gender, etiology of liver disease, Model for End-Stage Liver Disease score, Child-Pugh class, cold and warm ischemic times, ICU stay, duration of invasive mechanical, and use of noninvasive ventilation (NIV). We divided the patients into 3 groups: Group 1, (normal weight BMI 18.5-24.99), versus group 2 overweight-BMI 25-29.99; versus group 3, obese-BMI >= 30. Results. Groups 1, 2, and 3 had similar lengths of stay in the ICU, necessity of NIV as well as 6 month, 1- and 2-year survivals (P > .05). Conclusion. High BMI patients showed similar results to normal or overweight patients. Obesity should not be contraindication to liver transplantation.

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