4.1 Article Proceedings Paper

Coronary artery calcifications in hemodialysis patients and their correlation with the prevalence of erectile dysfunction

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TRANSPLANTATION PROCEEDINGS
卷 40, 期 1, 页码 77-80

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.transproceed.2007.11.046

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Introduction. Our aim in this study was to investigate the prevalence and correlation with coronary artery calcium scores (CACS) and erectile dysfunction (ED) among hemodialysis patients. Patients and methods. Thirty-five male patients with chronic renal failure were selected to participate in this study. All patients underwent examinations for CACS using 16-channel multidetector computed tomography. The presence and severity of ED were determined by calculating the erectile function domain of the self-administered International Index of Erectile Function (IIEF). Results. The patients' ages ranged from 22 to 78 with a mean of 51.6 years. The mean duration of hemodialysis was 75.7 months (range = 12 to 232). Twenty-six patients had a history of one or more systemic diseases. The prevalence of any level of ED was 82.9% for all hemodialysis patients, and severe ED, 40%. The CACS was significantly higher among patients with severe ED (P =.032). The IIEF-5 score was also shown to have a moderate negative correlation with the CACS (r = -.420, P =.012). Age, duration of hemodialysis, body mass index, diabetes mellitus, hypertension, coronary heart diseases, hyperlipidemia, thyroid disease, depression, tobacco consumption, and medication were not associated with the presence of ED (P >.05). Conclusion. ED is prevalent in hemodialysis patients. Although many possible factors contribute to ED, the severity of ED increases with greater CACS.

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