期刊
TRANSPLANT INFECTIOUS DISEASE
卷 12, 期 2, 页码 127-131出版社
WILEY
DOI: 10.1111/j.1399-3062.2010.00493.x
关键词
influenza A; H1N1; oseltamivir; pneumonia; kidney transplant
P>We report 2 cases of severe pneumonia due to the novel pandemic influenza A/H1N1 2009 in kidney transplant recipients. Our patients initially experienced influenza-like illness that rapidly progressed to severe pneumonia within 48 h. The patients became hypoxic and required non-invasive ventilation. The novel influenza A/H1N1 2009 was identified from their nasal swabs. These cases were treated successfully with a relatively high dose of oseltamivir, adjusted for their renal function. Clinical improvement was documented only after a week of antiviral therapy. Despite early antiviral treatment, we showed that morbidity following novel pandemic influenza A/H1N1 2009 infection is high among kidney transplant recipients.
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