期刊
TRANSFUSION CLINIQUE ET BIOLOGIQUE
卷 17, 期 3, 页码 131-137出版社
ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
DOI: 10.1016/j.tracli.2010.05.004
关键词
Exosomes; Reticulocytes; Membrane remodelling; Protein sorting; Erythropoiesis
资金
- CNRS
- University Montpellier II
- ANR [ANR-09-BLAN-0292-01]
- Agence Nationale de la Recherche (ANR) [ANR-09-BLAN-0292] Funding Source: Agence Nationale de la Recherche (ANR)
Multivesicular endosomes contain membrane vesicles which can be released into the extracellular environment as exosomes This review describes the role of exosome secretion in the remodeling of the red cell plasma membrane during the last stage of erythropoietic differentiation we propose that the exosome biogenesis involves several mechanisms of protein sorting and leads to partial or complete loss of membrane activities, in some cases in a regulated way (C) 2010 Elsevier Masson SAS All rights reserved
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