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CD34+cell subclasses and lymphocyte subsets in blood grafts collected after various mobilization methods in myeloma patients
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The EBMT activity survey 2008: impact of team size, team density and new trends
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Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice
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Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
Andrew Chow et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells
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Plerixafor and granulocyte-colony-stimulating factor (G-CSF) in patients with lymphoma and multiple myeloma previously failing mobilization with G-CSF with or without chemotherapy for autologous hematopoietic stem cell mobilization: the Austrian experience on a named patient program
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Beyond CD34+cell dose: impact of method of peripheral blood hematopoietic stem cell mobilization (granulocyte-colony-stimulating factor [G-CSF], G-CSF plus plerixafor, or cyclophosphamide G-CSF/granulocyte-macrophage [GM]-CSF) on number of colony-forming unit-GM, engraftment, and Day+100 hematopoietic graft function
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Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs
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Mobilization of peripheral blood stem cells for autologous transplant in non-Hodgkin's lymphoma and multiple myeloma patients by plerixafor and G-CSF and detection of tumor cell mobilization by PCR in multiple myeloma patients
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Innate immunity as orchestrator of stem cell mobilization
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The endosteal 'osteoblastic' niche and its role in hematopoietic stem cell homing and mobilization
J-P Levesque et al.
LEUKEMIA (2010)
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
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BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells
Pablo Ramirez et al.
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Improving stem cell mobilization strategies: future directions
W. Bensinger et al.
BONE MARROW TRANSPLANTATION (2009)
A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a European phase II study
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Phase III Prospective Randomized Double-Blind Placebo-Controlled Trial of Plerixafor Plus Granulocyte Colony-Stimulating Factor Compared With Placebo Plus Granulocyte Colony-Stimulating Factor for Autologous Stem-Cell Mobilization and Transplantation for Patients With Non-Hodgkin's Lymphoma
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Impaired mobilization of hematopoietic stem/progenitor cells in C5-deficient mice supports the pivotal involvement of innate immunity in this process and reveals novel promobilization effects of granulocytes
H. M. Lee et al.
LEUKEMIA (2009)
Increased numbers of circulating hematopoietic stem/progenitor cells are chronically maintained in patients treated with the CD49d blocking antibody natalizumab
Halvard Bonig et al.
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Plasmin therapy enhances mobilization of HPCs after G-CSF
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Granulocyte Colony-Stimulating Factor Induces Osteoblast Apoptosis and Inhibits Osteoblast Differentiation
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JOURNAL OF BONE AND MINERAL RESEARCH (2008)
Factors affecting autologous peripheral blood stem cell collection in patients with relapsed or refractory diffuse large cell lymphoma and Hodgkin lymphoma: A single institution result of 168 patients
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AMD3100 plus G-CSF can successfully mobilize CD34+cells from non-Hodgkin's lymphoma, Hodgkin's disease and multiple myeloma patients previously failing mobilization with chemotherapy and/or cytokine treatment: compassionate use data
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Characterization of the molecular pharmacology of AMD3100: A specific antagonist of the G-protein coupled chemokine receptor, CXCR4
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Osteoclasts degrade endosteal components and promote mobilization of hematopoietic progenitor cells
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AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates
A Larochelle et al.
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G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow
CL Semerad et al.
BLOOD (2005)
Rapid mobilization of murine and human hematopoietic stem and progenitor cells with AMD3100, a CXCR4 antagonist
HE Broxmeyer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Augmented mobilization and collection of CD34+ hematopoietic cells from normal human volunteers stimulated with granulocyte-colony-stimulating factor by single-dose administration of AMD3100, a CXCR4 antagonist
WC Liles et al.
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Prediction of mobilisation failure in patients with non-Hodgkin's lymphoma
T Kuittinen et al.
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CD44 and hyaluronic acid cooperate with SDF-1 in the trafficking of human CD34+ stem/progenitor cells to bone marrow
A Avigdor et al.
BLOOD (2004)
Mobilization studies in mice deficient in either C3 or C3a receptor (C3aR) reveal a novel role for complement in retention of hematopoietic stem/progenitor cells in bone marrow
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BLOOD (2004)
Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor - Transfer of binding site to the CXCR3 receptor
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Salvage therapy with an outpatient DHAP schedule followed by PBSC transplantation in 79 lymphoma patients: an intention to mobilize and transplant analysis
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EUROPEAN JOURNAL OF HAEMATOLOGY (2004)
Granulocyte colony-stimulating factor induces the release in the bone marrow of proteases that cleave c-KIT receptor (CD117) from the surface of hematopoietic progenitor cells
JP Lévesque et al.
EXPERIMENTAL HEMATOLOGY (2003)
Poor mobilization of peripheral blood stem cells is a risk factor for worse outcome in lymphoma patients undergoing autologous stem cell transplantation
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Human CD34+CXCR4- sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation
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G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
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Mobilization by either cyclophosphamide or granulocyte colony-stimulating factor transforms the bone marrow into a highly proteolytic environment
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Vascular cell adhesion molecule-1 (CD 106) is cleaved by neutrophil proteases in the bone marrow following hematopoietic progenitor cell mobilization by granulocyte colony-stimulating factor
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Rapid and efficient homing of human CD34+CD38-/lowCXCR4+ stem and progenitor cells to the bone marrow and spleen of NOD/SCID and NOD/SCID/B2mnull mice
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Combining G-CSF with a blockade of adhesion strongly improves the reconstitutive capacity of mobilized hematopoietic progenitor cells
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