相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Idiosyncratic drug reactions: Past, present, and future
Jack Uetrecht
CHEMICAL RESEARCH IN TOXICOLOGY (2008)
Role of Mitochondria in Drug-Induced Cholestatic Injury
George E. N. Kass et al.
CLINICS IN LIVER DISEASE (2008)
NADPH-dependent covalent binding of [3H]paroxetine to human liver microsomes and S-9 fractions:: Identification of an electrophilic quinone metabolite of paroxetine
Sabrina X. Zhao et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2007)
Reduced mitochondrial coenzyme Q10 levels in HepG2 cells treated with high-dose simvastatin: A possible role in statin-induced hepatotoxicity?
S. Tavintharan et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Gene expression profiling of extracellular matrix as an effector of human hepatocyte phenotype in primary cell culture
Jeanine L. Page et al.
TOXICOLOGICAL SCIENCES (2007)
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests:: Report of an ECVAM Workshop
David Kirkland et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2007)
Antioxidant effect of 2-hydroxy-4-methoxy benzoic acid on ethanol-induced hepatotoxicity in rats
Nadana Saravanan et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2007)
Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver
Abir Kasdallah-Grissa et al.
LIFE SCIENCES (2007)
Mitochondrial abnonnalities - A link to idiosyncratic drug hepatotoxicity?
Urs A. Boelsterli et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2007)
Primary hepatocytes: Current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies
Nicola J. Hewitt et al.
DRUG METABOLISM REVIEWS (2007)
High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening
P. J. O'Brien et al.
ARCHIVES OF TOXICOLOGY (2006)
Let there be bile - Understanding hepatic injury in cholestasis
Ronald J. Sokol et al.
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION (2006)
Current concepts - Drug-related hepatotoxicity
VJ Navarro et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport
Yi-an Bi et al.
DRUG METABOLISM AND DISPOSITION (2006)
Mechanisms of drug-induced liver injury
MP Holt et al.
AAPS JOURNAL (2006)
Can pharmacogenetics help rescue drugs withdrawn from the market?
Rashmi R. Shah
PHARMACOGENOMICS (2006)
The use of receiver operating characteristic curves in biomedical informatics
TA Lasko et al.
JOURNAL OF BIOMEDICAL INFORMATICS (2005)
Idiosyncratic drug hepatotoxicity
N Kaplowitz
NATURE REVIEWS DRUG DISCOVERY (2005)
Influence of Matrigel-overlay on constitutive and inducible expression of nine genes encoding drug-metabolizing enzymes in primary human hepatocytes
K Gross-Steinmeyer et al.
XENOBIOTICA (2005)
Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review
JLCM Dorne et al.
FOOD AND CHEMICAL TOXICOLOGY (2005)
Idiosyncratic liver injury: Challenges and approaches
PB Watkins
TOXICOLOGIC PATHOLOGY (2005)
Recognizing drug-induced liver injury: Current problems, possible solutions
WM Lee et al.
TOXICOLOGIC PATHOLOGY (2005)
Why drugs fail - A study on side effects in new chemical entities
D Schuster et al.
CURRENT PHARMACEUTICAL DESIGN (2005)
Tamoxifen cytotoxicity in hepatoblastoma cells stably transfected with human CYP3A4
A Holownia et al.
BIOCHEMICAL PHARMACOLOGY (2004)
Effects of human pharmaceuticals on cytotoxicity, EROD activity and ROS production in fish hepatocytes
N Laville et al.
TOXICOLOGY (2004)
P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: Relevance to the hepatobiliary disposition of a model opioid peptide
KA Hoffmaster et al.
PHARMACEUTICAL RESEARCH (2004)
Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential
JJ Xu et al.
CHEMICO-BIOLOGICAL INTERACTIONS (2004)
Medical progress: Drug-induced hepatotoxicity
WM Lee
NEW ENGLAND JOURNAL OF MEDICINE (2003)
Characterisation of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. II. Spheroid cell spreading inhibition as a new cytotoxic marker
JS Xu et al.
TOXICOLOGY AND APPLIED PHARMACOLOGY (2003)
A review of the common properties of drugs with idiosyncratic hepatotoxicity and the multiple determinant hypothesis for the manifestation of idiosyncratic drug toxicity
AP Li
CHEMICO-BIOLOGICAL INTERACTIONS (2002)
Cytochrome P450 3A4-mediated bioactivation of raloxifene: Irreversible enzyme inhibition and thiol adduct formation
Q Chen et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2002)
Mechanisms of NSAID-induced hepatotoxicity - Focus on nimesulide
UA Boelsterli
DRUG SAFETY (2002)
Concordance of the toxicity of pharmaceuticals in humans and in animals
H Olson et al.
REGULATORY TOXICOLOGY AND PHARMACOLOGY (2000)
分享论文
