期刊
TISSUE ENGINEERING PART B-REVIEWS
卷 19, 期 4, 页码 380-390出版社
MARY ANN LIEBERT, INC
DOI: 10.1089/ten.teb.2012.0443
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- SmartMix Program of the Netherlands Ministry of Economic Affairs
- Netherlands Ministry of Education, Culture, and Science
Poly(lactic-co-glycolic acid) (PLGA) is the most often used synthetic polymer within the field of bone regeneration owing to its biocompatibility and biodegradability. As a consequence, a large number of medical devices comprising PLGA have been approved for clinical use in humans by the American Food and Drug Administration. As compared with the homopolymers of lactic acid poly(lactic acid) and poly(glycolic acid), the copolymer PLGA is much more versatile with regard to the control over degradation rate. As a material for bone regeneration, the use of PLGA has been extensively studied for application and is included as either scaffolds, coatings, fibers, or micro-and nanospheres to meet vaious clinical requirements.
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