4.2 Article

Culture of Neural Cells and Stem Cells on Graphene

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出版社

KOREAN TISSUE ENGINEERING REGENERATIVE MEDICINE SOC
DOI: 10.1007/s13770-013-0384-6

关键词

graphene; neural cell; mesenchymal stem cell; induced pluripoten stem cell; neural stem cell; cytotoxicity

资金

  1. Korean Health 21 R&D Project, Ministry of Health and Welfare, Republic of Korea [A100443]
  2. Korea Health Promotion Institute [HI10C0429010013] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Graphene, as a new potential biocompatible biomaterial, retains some unique properties such as high electrical conductivity, elasticity and good molecule absorption. It has tremendous potential for a wide variety of biomedical applications. Even though studies on graphene-based nanomaterials are still at a nascent stage, graphene has been a matter of common interest in tissue engineering and regenerative medicine. In this review, we summarize the characteristics of graphene that could impose biological effects on cells. We discuss in detail the exploration of graphene when applied on neural cells and stem cells; how it affects cell behavior and differentiation. We then present the results from cytotoxicity studies on graphene and its derivatives.

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