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Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: this dissociation regulates P2X7 pore formation
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Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice
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Inhibition of P2X(7) receptors by divalent cations: old action and new insight
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Palmitoylation of the P2X7 receptor, an ATP-gated channel, controls its expression and association with lipid rafts
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Autocrine regulation of T-cell activation by ATP release and P2X(7) receptors
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The P2X7 Receptor Drives Microglial Activation and Proliferation: A Trophic Role for P2X7R Pore
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Crystal structure of the ATP-gated P2X4 ion channel in the closed state
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The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types
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Regulation of P2X(7) gene transcription
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Genetics of the P2X7 receptor and human disease
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Physiological and pathological functions of P2X7 receptor in the spinal cord
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P2X7 receptors regulate multiple types of membrane trafficking responses and non-classical secretion pathways
Yan Qu et al.
PURINERGIC SIGNALLING (2009)
ATP-induced P2X(7)-associated uptake of large molecules involves distinct mechanisms for cations and anions in macrophages
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JOURNAL OF CELL SCIENCE (2008)
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way
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Purinergic receptors in the endocrine and exocrine pancreas
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Effect of the purinergic receptor P2X7 on Chlamydia infection in cervical epithelial cells and vaginally infected mice
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JOURNAL OF IMMUNOLOGY (2007)
Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment
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Discovery of P2X7 receptor-selective antagonists offers new insights into P2X7 receptor function and indicates a role in chronic pain states
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P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells
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A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis
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ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
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P2X7 nucleotide receptors mediate blebbing in osteoblasts through a pathway involving lysophosphatidic acid
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A truncated P2X7 receptor variant (P2X7-j) endogenously expressed in cervical cancer cells antagonizes the full-length P2X7 receptor through hetero-oligomerization
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor
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Cryopyrin activates the inflammasome in response to toxins and ATP
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A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages
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JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
P2X7 receptor-dependent ATP-induced shedding of CD27 in mouse lymphocytes
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Pseudoapoptosis induced by brief activation of ATP-gated P2X7 receptors
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human epidermal and monocyte-derived Langerhans cells express functional P2X7 receptors
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Characterization of a functional P2X7-like receptor in cerebellar granule neurons from P2X7 knockout mice
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Identification and characterization of splice variants of the human P2X7 ATP channel
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Glu496 to Ala polymorphism in the P2X7 receptor impairs ATP-induced IL-1β release from human monocytes
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P2X7 receptor inhibition improves recovery after spinal cord injury
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An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor
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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
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A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of mycobacteria
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NAD-induced T cell death: ADP-ribosylation of cell surface proteins by ART2 activates the cytolytic P2X7 purinoceptor
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Deletion of the P2X7 nucleotide receptor reveals its regulatory roles in bone formation and resorption
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P2X7 receptor cell surface expression and cytolytic pore formation are regulated by a distal C-terminal region
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JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Proteomic and functional evidence for a P2X7 receptor signalling complex
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Rapid secretion of interleukin-1β by microvesicle shedding
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ATP stimulates human macrophages to kill intracellular virulent Mycobacterium tuberculosis via calcium-dependent phagosome-lysosome fusion
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JOURNAL OF IMMUNOLOGY (2001)
A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor
BJ Gu et al.
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ATP-stimulated release of interleukin (IL)-1β and IL-18 requires priming by lipopolysaccharide and is independent of caspase-1 cleavage
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