期刊
THORACIC AND CARDIOVASCULAR SURGEON
卷 57, 期 5, 页码 309-311出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-2008-1038634
关键词
Thoracic surgery; heart and lung transplantation; cardiovascular surgery
The overproduction of reactive oxygen species plays an important role in the cascade of events during lung ischemia-reperfusion leading to graft failure. An evaluation of the peripheral markers of oxidative stress and antioxidant enzyme activities was carried out after reperfusion in a rat lung transplant model. The decrease in lipid peroxidation immediately after transplantation (p < 0.05) may suggest an adaptative response and/or a protective effect of low potassium dextran against lipid peroxidation through natural scavenging mechanisms.
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