Models for the basis of enantioselection in palladium mediated C-H activation reactions

Models are proposed to account for the basis of enantioselection in cyclopalladation reactions, which result in the formation of planar chiral palladacycles. This analysis is extended to a palladium catalysed enantioselective C-H activation reaction proceeding via the intermediacy of a chiral palladacycle. (C) 2010 Elsevier Ltd. All rights reserved.