期刊
TETRAHEDRON-ASYMMETRY
卷 20, 期 19, 页码 2193-2199出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetasy.2009.08.008
关键词
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资金
- Universite Paris-Sud
- CNRS
- Servier Company
Chiral-2-substituted indolines are an important class of compounds with numerous applications in organic synthesis and as constituents of a number of biologically active molecules. Consequently, there has been a continued interest in the development of efficient methods for the syntheses of this class of chiral compounds. In this review, a detailed survey of the important efforts toward the synthesis of enantioenriched 2-substituted indolines by means of the kinetic resolution or the use of a chiral auxiliary in stoichiometric or catalytic processes is provided. The resolution of racemic mixtures through diastereomeric separation is not considered in the article. (C) 2009 Elsevier Ltd. All rights reserved.
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