4.4 Article

Nano-copper catalyzed three-component reaction to construct 1,4-substituted 1,2,3-triazoles

期刊

TETRAHEDRON LETTERS
卷 55, 期 14, 页码 2312-2316

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.02.114

关键词

Copper nanoparticles; Phenylacetylene; Cycloaddition; Click chemistry; Multicomponent reaction

资金

  1. Natural Science Foundation of China [20702042, 21262028]
  2. Program for Changjiang Scholars and Innovative Research Teams in Universities of the Ministry of Education of China [IRT1177]
  3. Natural Science Foundation of Gansu Province [1208RJZA140]

向作者/读者索取更多资源

Three-component reaction of alkyl halides, sodium azide with terminal alkynes can be catalyzed by nano-copper particles under ambient conditions. A series of 1,4-disubstituted-1,2,3-triazoles were obtained regioselectively by this one-pot strategy. Nano copper can be reused at least three times without significant deactivation. (C) 2014 Elsevier Ltd. All rights reserved.

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