期刊
TETRAHEDRON LETTERS
卷 55, 期 4, 页码 954-958出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.12.055
关键词
Friedel-Crafts reaction; Indole; Enamide; Vinyl ether; Triarylaminium salt
资金
- National Natural Science Foundation of China [21262029, 21002080]
- Natural Science Foundation of Gansu Province [1107RJYA026]
Commercially available stable radical cation triarylaminium salt can be used as an efficient initiator for Friedel-Crafts reaction of indoles with enamides to regioselectively construct complex indole derivatives and for double Friedel-Crafts reaction of indoles with vinyl ethers to offer 3,3'-Bis(indolyl)alkane derivatives. The ready availability of the starting materials and the usefulness of the products make this strategy attractive. (C) 2013 Elsevier Ltd. All rights reserved.
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