期刊
TETRAHEDRON LETTERS
卷 55, 期 11, 页码 1905-1908出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.01.133
关键词
Diketopiperazine; Fmoc deprotection; Intramolecular cyclization; Amide formation; Neuroprotection
资金
- Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy
We report a one-step protocol for the general synthesis of 2,5-diketopiperazines from an Fmoc-protected amino acid and an amino acid ester. The application of the method is highlighted by rapid and efficient preparation of various 2,5-diketopiperazines. (c) 2014 Elsevier Ltd. All rights reserved.
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