期刊
TETRAHEDRON LETTERS
卷 55, 期 2, 页码 329-332出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.11.016
关键词
Three-component, domino reactions 3-Methyl-1-aryl-1H-pyrazol-5-amines, N-methyl-1-(methylthio)-2-nitroprop-1-en-1-amine; Pyrazolo[3,4-b]pyridines; L-Proline
资金
- Department of Science and Technology, New Delhi [SR/S1/OC/-50/2011]
- University Grants Commission, New Delhi
- CSIR, New Delhi
A series of novel N,3-dimethyl-5-nitro-1-aryl-1H-pyrazolo[3,4-b]pyridin-6-amines was obtained in good yields from the domino reactions of N-methyl-1-(methylthio)-2-nitroprop-1-en-1-amine, aromatic aldehydes, and 3-methyl-1-aryl-1H-pyrazol-5-amines in ethanol in the presence of green catalyst, L-proline. This transformation involves the formation of two C-C and one C-N bonds leading to the creation of a six-membered ring in a one-pot operation. (C) 2013 Elsevier Ltd. All rights reserved.
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