期刊
TETRAHEDRON LETTERS
卷 55, 期 1, 页码 244-247出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.11.003
关键词
BODIPY; Azide-alkyne click reaction; Fluorescence; Solvatochromic properties; Cell imaging
资金
- IISER Pune
- DAE [2010/20/37C/6/BRNS/2480]
- CSIR
- UGC
The design, synthesis, and photophysical properties of new BODIPY-based fluorogenic 'click on' dyes are reported. CuAAC reaction of non-fluorescent BODIPY azide with a series of non-fluorescent alkyne molecules resulted in fluorescent triazoles which displayed up to 532-fold enhancement of fluorescence in the red region. Imaging studies confirmed the general trend of cell permeability and a cholesterol linked derivative exhibited selective localization into intracellular membranes. (C) 2013 Elsevier Ltd. All rights reserved.
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