期刊
TETRAHEDRON LETTERS
卷 55, 期 42, 页码 5808-5812出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.08.084
关键词
Benzoheterocyclic compounds; Solid-state melt reaction; Anti-tumor agents
资金
- DST-SERB
- CSIR
An efficient protocol for the synthesis of biologically active benzoheterocyclic compounds such as benzothiazoles, benzimidazoles, benzospirothiazoles, and quinoxaline scaffolds have been accomplished via solid state melt reaction (SSMR) with excellent yields. The new protocol does not require any catalyst, solvent, and workup. Two anti-tumor agents have been prepared to demonstrate the application of this new method. (C) 2014 Elsevier Ltd. All rights reserved.
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