Rapid synthesis of aryl sulfides through metal-free C-S coupling of thioalcohols with diaryliodonium salts

An efficient, general, and highly selective method for the synthesis of aryl sulfides has been developed through metal-free, direct C-S coupling from thioalcohols and diaryliodonium salts. Significantly, the reaction took only 10 min to complete and produced high yields at room temperature. Thus, this methodology proves its value as a versatile synthetic choice for a broad range of aryl sulfides, producing good to excellent yields. (C) 2014 Elsevier Ltd. All rights reserved.