期刊
TETRAHEDRON LETTERS
卷 55, 期 9, 页码 1640-1643出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.01.090
关键词
Monascus azaphilone pigment biosynthesis; Monascus purpureus; Knoevenagel aldol condensation; Targeted inactivation of mpp7
资金
- Basic Science Research Program through the National Research Foundation of Korea (NRF)
- Ministry of Education [2011-0021169, 2013R1A1A2059458]
Targeted inactivation of the mpp7 gene in the Monascus azaphilone pigment (MAzP) biosynthetic gene cluster resulted in the accumulation of monasfluol A (7) and B (8), of which the latter was a novel compound, and the abolition of the main MAzPs. It is thus proposed that 7 and 8 are the products of nonenzymatic Knoevenagel condensation followed by a reduction and that Mpp7 assists in regioselective Knoevenagel aldol condensation during MAzP biosynthesis. (C) 2014 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据