期刊
TETRAHEDRON LETTERS
卷 55, 期 40, 页码 5539-5543出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2014.08.041
关键词
Suzuki cross-coupling; Phosphine-free; Pd nanoparticles; Polyphenols; Sustainable synthesis
资金
- CSIR, New Delhi [CSC-107]
A mild and selective protocol has been developed for the palladium-catalyzed phosphine-free Suzuki cross-coupling reaction of aryl bromides with arylboronic acids in aqueous tea extract at room temperature. It is noteworthy that the aqueous tea extract plays an important role in the reaction, and various functional groups are tolerated under the optimized conditions. The reactions proceeded with very good chemoselectivity in favor of the bromo instead of the chloro group even at higher temperatures. Furthermore, this protocol could be applied to the cross-coupling of 4-bromoindole without protecting the base sensitive amine group with arylboronic acids in moderate to excellent yields. (C) 2014 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据