4.4 Article

Copper-catalyzed cyanation of aryl iodide with the combined cyanide source of urea and DMSO

期刊

TETRAHEDRON LETTERS
卷 54, 期 38, 页码 5250-5252

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.07.090

关键词

Copper-catalyzed; Cyanation; Aryl iodide; Nitriles

资金

  1. National Natural Science Foundation of China [21272178]
  2. Natural Science Foundation of Zhejiang Province [LY12B02010]

向作者/读者索取更多资源

A simple copper-catalyzed cyanation of aryl iodide with the combination of urea and dimethyl sulfoxide as a cyanide source is achieved, providing nitriles in moderate to good yields. This new approach represents an exceedingly practical and safe method for the synthesis of aryl nitriles. (C) 2013 Elsevier Ltd. All rights reserved.

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