期刊
TETRAHEDRON LETTERS
卷 54, 期 50, 页码 6937-6939出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.10.049
关键词
H2S; Fluorescence probe; Cellular bioimaging
资金
- Beijing University of Chemical Technology Start-up Grant (985 project platform)
- Fundamental Research Funds for the Central Universities [zz1305]
A FRET-based fluorescence probe was developed for selective detection of H2S in aqueous buffer and inside living cells. For this probe, the FRET probe could be cleaved by H2S, and the fluorescence of FRET donor is released. The probe is highly selective to H2S over other biologically relevant species to give color change for naked eye observation. Confocal imaging indicated that the probe could monitor intracellular H2S level changes. (C) 2013 Elsevier Ltd. All rights reserved.
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