期刊
TETRAHEDRON LETTERS
卷 54, 期 11, 页码 1401-1404出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.12.126
关键词
Chan Evans Lam cross-coupling; Arylboronic acids; Selectivity; O-arylation; Pyridin-2-ones
资金
- National Natural Science Foundation of China [81172936, 21102046]
- Fundamental Research Funds for the Central Universities
- Laboratory of Organic Functional Molecules, the Sino-French Institute of ECNU
A practical and mild strategy has been developed for the selective O-arylation on C-6 substituted pyridin-2-ones with a series of arylboronic acids, using Cu(OTf)(2) as the catalyst, DABCO as the ligand, Et3N as the base, and K2HPO4 as the additive. This method affords O-arylated pyridin-2-ones with good selectivity and yields (C) 2013 Elsevier Ltd. All rights reserved.
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