期刊
TETRAHEDRON LETTERS
卷 54, 期 48, 页码 6490-6493出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2013.09.077
关键词
Alkylation; Alcohols; Methylquinoline; Platinum
资金
- MEXT program 'Elements Strategy Initiative to Form Core Research Center', Japan
- Grants-in-Aid for Scientific Research [25106010] Funding Source: KAKEN
Supported metal nanoparticle catalysts are studied for alkylation of 2-methylquinoline with benzyl alcohol under additive-free conditions in N-2 atmosphere. Among various metal-loaded Al2O3 catalysts and supported Pt catalysts, Pt metal nanocluster loaded-Al2O3 pre-reduced in H-2 at 500 degrees C shows highest yield (82%) of the product (2-phenethyl-quinoline). The catalyst is reusable, shows higher turnover number than a previous homogeneous catalyst, and shows good to moderate yield for alkylation of 2-methylquinoline with various alcohols. The reaction is driven by the borrowing-hydrogen pathway, in which aldehyde formed by dehydrogenation of alcohol undergoes aldol condensation with 2-methylquinoline to give the alkene intermediate which is finally hydrogenated by Pt-H species. (C) 2013 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据