4.4 Article

Biocatalytic asymmetric aldol reaction in buffer solution

期刊

TETRAHEDRON LETTERS
卷 54, 期 8, 页码 945-948

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.12.022

关键词

Biocatalysis; Asymmetric cross-aldol reaction; Bovine pancreatic lipase; Buffer solution

资金

  1. National Natural Science Foundation of China [21001077, 20121001]
  2. Program for Changjiang Scholars and Natural Science Foundation of Jiangxi [20114BAB213003, 20122BAB203006]

向作者/读者索取更多资源

A green and convenient protocol has been developed for asymmetric cross-aldol reaction. In this Letter, bovine pancreatic lipase (BPL) was first reported to catalyze the aldol reaction and acidic buffer was first used for promiscuous enzymatic aldol reaction. (C) 2012 Elsevier Ltd. All rights reserved.

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