期刊
TETRAHEDRON LETTERS
卷 53, 期 12, 页码 1479-1484出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.01.042
关键词
Bi(NO3)(3)center dot 5H(2)O; Heterocycles; Highly functionalized piperidines; One-pot synthesis; Tandem reaction; Multicomponent reaction; Room temperature; Environmentally benign
资金
- UGC, New Delhi
A simple, straightforward, and highly efficient diastereoselective multicomponent one-pot synthesis of a series of pharmaceutically interesting functionalized piperidine derivatives has been developed based on a low-cost and environmentally benign Bi(NO3)(3)center dot 5H(2)O catalyst via tandem reactions of 1,3-dicarbonyl compounds, aromatic aldehydes, and various amines in ethanol at room temperature. High atom-economy, good yields, eco-friendliness, and mild reaction conditions are some of the important features of this protocol. (C) 2012 Elsevier Ltd. All rights reserved.
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