期刊
TETRAHEDRON LETTERS
卷 53, 期 6, 页码 632-636出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.11.113
关键词
Click chemistry; Solid-phase synthesis; Penicillins; Peptides
资金
- CONICET
- ANPCyT
- UNR from Argentina
An efficient and versatile methodology for the preparation of valuable triazolyl aminoacyl (peptidyl) penicillins is described. Solid-phase Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition was used as the key step showing general applicability and excellent regioselectivity either with CuI or [Cu(CH3CN)(4)]PF6 as Cu(I) source. (C) 2011 Elsevier Ltd. All rights reserved.
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