期刊
TETRAHEDRON LETTERS
卷 53, 期 14, 页码 1710-1712出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.01.077
关键词
Briareum; Briarenolide; Briarane; Superoxide anion; Elastase
资金
- National Dong Hwa University
- National Museum of Marine Biology and Aquarium [100100101, 100200311]
- Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University [00C-0302-05]
- Taiwan Department of Health Clinical Trial and Research Center of Excellence [DOH 101-TD-B-111-004]
- National Science Council, Taiwan [NSC 100-2325-B-291-001, 98-2320-B-291-001-MY3]
A novel 2-ketobriarane diterpenoid, briarenolide E (1), was isolated from an octocoral Briareum sp. The structure of briarane 1 was elucidated by interpretations of spectral data. Compound 1 displayed modestly inhibitory effects on the generation of superoxide anions and the release of elastase by human neutrophils. (C) 2012 Elsevier Ltd. All rights reserved.
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