Pd(II)-catalyzed intramolecular C-H activation/C-C cross coupling for the synthesis of carbazoles from diaryl acetamides

Pd(II)-catalyzed intramolecular C-H activation/C-C cross coupling within N,N-diphenyl-acetamides allows the efficient formation of differently substituted carbazoles. In this cross-dehydrogenative coupling, many different functional groups are tolerated and the starting material N,N-diphenyl-acetamides can be easily prepared in one step from commercially available acetanilides and iodobenzenes. (C) 2011 Elsevier Ltd. All rights reserved.