期刊
TETRAHEDRON LETTERS
卷 53, 期 43, 页码 5739-5741出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2012.08.013
关键词
1,2-Aminoalcohol; Epoxide; Chlorohydrin; NaHMDS; Epoxide opening; Regio-selective
A simple and efficient procedure for the regio-selective synthesis of 1,2-aminoalcohols from terminal epoxides and chlorohydrins by using NaHMDS as the source of amine is reported. The wider scope and utility of this method is demonstrated. (C) 2012 Elsevier Ltd. All rights reserved.
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