Efficient Fe/I2/NaI mediated synthesis of alkenyl iodides through direct coupling of alcohols and alkynes

A new and efficient method for the synthesis of alkenyl iodides through direct coupling of alcohols and alkynes has been developed in the presence of iron powder, I-2, and NaI. This methodology not only provides an attractive approach to alkenyl iodides, but also expands the application of iron in synthetic chemistry. (C)2011 Elsevier Ltd. All rights reserved.