期刊
TETRAHEDRON LETTERS
卷 52, 期 7, 页码 809-812出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.12.039
关键词
Multi-component reactions; Biginelli reaction; N,N '-Dichlorobis(2,4,6-trichloropheny)urea (CC-2) Dihydropyrimidones; Benzimidazoles; Benzothiazoles
A simple and efficient method for the synthesis of 3,4-dihydropyrimidin-2-(1H)one and benzo[4,5]imidazo/thioazo[1,2-a]pyrimidine derivatives has been described using N,N'-dichlorobis(2,4,6-trichlorophenyl)urea (CC-2) as a new reagent. This method is found to be efficient and convenient for the synthesis of pyrimidone and pyrimidine derivatives. (C) 2010 Elsevier Ltd. All rights reserved.
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