期刊
TETRAHEDRON LETTERS
卷 52, 期 41, 页码 5327-5332出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.08.019
关键词
Multicomponent reactions; Pyran annulated heterocyclic derivatives; 4-Hydroxy-coumarin; 4-(Dimethylamino)pyridine (DMAP)
资金
- CSIR, New Delhi
- UGC, New Delhi
The one-pot three-component reaction for the synthesis of pyran annulated heterocycles is reported by condensing aromatic aldehydes, ethyl cyanoacetate, or malononitrile and C-H activated acidic compounds in the presence of catalytic amount of 4-(dimethylamino)pyridine (DMAP) in ethanol under reflux conditions. The significant features of the present protocol are simple, environmentally benign, high yields, non-aqueous work-up procedure, no chromatographic separation and recyclability of the catalyst. (C) 2011 Elsevier Ltd. All rights reserved.
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