4.4 Article

Synthesis of methyl (5Z,8Z,10E,12E,14Z)-eicosapentaenoate

期刊

TETRAHEDRON LETTERS
卷 52, 期 10, 页码 1057-1059

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.12.078

关键词

Bosseopentaenoic acid; MIDA-protected boronate ester; Polyunsaturated fatty acid; Conjugated Z,E,E,Z-tetraene

资金

  1. University of Oslo

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The first total synthesis of methyl (5Z,8Z,10E,12E,14Z)-eicosapentaenoate has been achieved in seven steps and in 16% overall yield. The synthesis confirmed the assigned structure of this polyunsaturated natural product. (C) 2010 Elsevier Ltd. All rights reserved.

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