Synthesis of libraries of quinoxalines through eco-friendly tandem oxidation-condensation or condensation reactions

A facile and expeditious solid-phase sythesis of libraries of quinoxalines promoted on KF-alumina surface via tandem oxidation-condensation or condensation reactions is reported. The reaction protocol is operationally simple and mild. Moreover, solvent-free reaction condition makes the reaction procedure eco-friendly and economically viable. (C) Elsevier Ltd. All rights reserved.