期刊
TETRAHEDRON LETTERS
卷 52, 期 3, 页码 465-467出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.11.100
关键词
-
资金
- NSFC [30860342, 20762013]
- NSFYN [2009cc017, 2008cd063]
A facile synthesis of tetracyclo-isocoumarins based on the AcOH-catalyzed cyclocondensation and rearrangement reaction between heterocyclic ketene aminals and 2,2-dihydroxy-2H-indene-1,3-dione is described. This method provides direct access to tetacyclo-isocoumarins, a class of compounds with potential broad spectrum biological activities. (C) 2010 Elsevier Ltd. All rights reserved.
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