期刊
TETRAHEDRON LETTERS
卷 52, 期 44, 页码 5736-5739出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2011.07.092
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资金
- National Natural Science Foundation of China [20932002]
- National Basic Research Program of China (973 Program) [2011CB808600]
- Ministry of Education of China [20090172110014]
- Guangdong Natural Science Foundation [10351064101000000, 8451064101000236]
An efficient procedure for regio- and stereoselective synthesis of a series of conjugated enynes by a simple Pd-catalyzed cross-coupling reaction of unactivated ethylenes and ethynyl bromide has been developed. The reaction proceeds smoothly in DMF to give the corresponding products in good to excellent yields. The protocol can tolerate a broad range of functional groups on the substrates. (C) 2011 Elsevier Ltd. All rights reserved.
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