Microwave-assisted Suzuki reaction catalyzed by Pd(0)-PVP nanoparticles

Suzuki cross-coupling reaction was successfully carried out in ethanol utilizing a palladium colloidal solution stabilized by polyvinylpyrrolidone (PVP). High isolated yields (75-97%) to biaryls were obtained using different bases, aryl halides, and aryl boronic acids with a small loading of the palladium catalyst. Pd(0)-PVP nanoparticles with 3-6 nm of medium diameter were prepared from Pd(OAc)(2) in the presence of the stabilizer PVP using methanol as the reducing agent. (C) 2010 Elsevier Ltd. All rights reserved.