The stereoselective total synthesis of (+)-garvensintriol

A simple and highly efficient stereoselective total synthesis of (+)-garvensintriol, isolated from the stem bark of Goniothalamas arvensis, is described using Sharpless kinetic resolution, MacMillan, alpha-hydroxylation, and Horner-Wadsworth-Emmons olefination as the key steps. (C) 2010 Elsevier Ltd. All rights reserved.