期刊
TETRAHEDRON LETTERS
卷 51, 期 42, 页码 5550-5554出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.08.039
关键词
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资金
- King Abdullah University of Science and Technology (KAUST) [KUS-11-006-02]
- NIH-NIGMS [R01 GM 080269-01]
- German Academic Exchange Service (DAAD)
- Abbott Laboratories
- Amgen
- Gordon and Betty Moore Foundation
- Caltech
Herein an efficient and direct copper-catalyzed coupling of oxazoline-containing aryl bromides with electron-deficient secondary phosphine oxides is reported. The resulting tertiary phosphine oxides can be reduced to prepare a range of PHOX ligands. The presented strategy is a useful alternative to known methods for constructing PHOX derivatives. (C) 2010 Elsevier Ltd. All rights reserved.
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