Highly functionalised 3,4,5-trisubstituted 1,2,4-triazoles for future use as ligands in coordination polymers

An optimised synthesis of 3,4,5-trisubstituted 1,2,4-triazoles, that can be used as linkers for metal organic frameworks (MOFs), is described. The substituents in 3- and 5-position of the triazole have a significant impact on the torsion angles between the aromatic rings and therefore influence on solubility and coordination behaviour of these ligands. (C) 2009 Elsevier Ltd. All rights reserved.