期刊
TETRAHEDRON LETTERS
卷 51, 期 37, 页码 4866-4869出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2010.07.041
关键词
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资金
- National Basic Research Program of China (973 Program) [2010CB126101]
- Shanghai Foundation of Science of Technology [09391911800]
- Shanghai Leading Academic Discipline Project [B507]
A novel synthesis of 2-trifluoromethyl-6-difluoromethylpyridine-3,5-dicarboxylates by three-component reaction of ethyl trifluoroacetoacetate, aldehydes, and ammonium acetate in the presence of K2CO3 under solvent-free conditions via sequential Hantzsch reaction/dehydration/dehydrofluorination in a one-pot process was described. (C) 2010 Elsevier Ltd. All rights reserved.
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