4.4 Article

1,3-Dipolar cycloaddition of arynes with azomethine imines: synthesis of 1,2-dihydropyrazolo[1,2-a]indazol-3(9H)-ones

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TETRAHEDRON LETTERS
卷 50, 期 28, 页码 4067-4070

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.04.102

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资金

  1. National Institute of General Medical Sciences [GM070620, GM079593]
  2. National Institutes of Health Kansas University Center of Excellence in Chemical Methodology and Library Development [P50 GM069663]

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A [3+2] 1,3-dipolar cycloaddition reaction of arynes with stable azomethine imines has been developed. The reaction rapidly assembles tricyclic pyrazoloindazolone derivatives in moderate yields under mild reaction conditions. (C) 2009 Elsevier Ltd. All rights reserved.

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