期刊
TETRAHEDRON LETTERS
卷 50, 期 24, 页码 2939-2942出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.03.208
关键词
Microwave irradiation; Montmorillonite K-10; Anilines; Cinnamaldehydes; Quinolines
资金
- University of Massachusetts Boston
A microwave-assisted solid acid-catalyzed synthesis of quinolines from anilines and cinnamaldehydes is described. Use of montmorillonite K-10 results in a one-pot process; the cyclization and oxidation steps readily take place in a domino approach. Reactions were completed in a matter of minutes and provided excellent yields. The efficient and ecofriendly catalyst and the convenience of the product isolation make this process an attractive alternative for the synthesis of these important heterocycles. (C) 2009 Elsevier Ltd. All rights reserved.
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