InCl3-catalyzed efficient one-pot synthesis of 2-pyrrolo-3′-yloxindoles

An InCl3-catalyzed one-pot synthesis of 2-pyrrolo-3'-yloxindoles was achieved via three-component reaction of 3-phenacylideneoxindole, beta-keto ester, and ammonium acetate at reflux by a sequential Michael addition followed by Paal-Knorr condensation. (C) 2009 Elsevier Ltd. All rights reserved.