期刊
TETRAHEDRON LETTERS
卷 50, 期 28, 页码 4025-4029出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.04.025
关键词
Michael addition reaction; beta-Ketoesters; DMAP-related organocatalyst; Aqueous media
A general and efficient protocol for the Michael addition reactions of beta-ketoesters in pure water has been developed. The reactions are successfully catalyzed by newly designed DMAP-related organocatalysts such as 4-(didecylamino)pyridine, and the desired Michael adducts are obtained in good to high yields (C) 2009 Elsevier Ltd. All rights reserved.
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