Palladium(II)/2,2′-bipyridine-catalyzed addition of arylboronic acids to N-tosyl-arylaldimines

A Pd(II)/NO2-bpy-catalyzed addition of the arylboronic acids to N-tosylaldimines to yield diarylmethylamines with moderate to excellent yield was developed. The use of bipyridines as the ligands is crucial in this reaction. The asymmetric version of the reaction also showed that a moderate high yield and ee value can be obtained using the pymox ligands. (C) 2009 Elsevier Ltd. All rights reserved.