4.4 Article

Exploitation of the catalytic efficacy of Mg/Al hydrotalcite for the rapid synthesis of 2-aminochromene derivatives via a multicomponent strategy in the presence of microwaves

期刊

TETRAHEDRON LETTERS
卷 50, 期 6, 页码 719-722

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PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2008.11.114

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2-Aminochromenes; Hydrotalcite; Microwaves

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Mg/Al hydrotalcite, a heterogeneous base catalyst, was found to be highly effective for the synthesis of 2-aminochromenes via a multicomponent reaction of aromatic aldehydes, malononitriles and 1-naphthol under microwaves. The reaction is rapid, clean and gives the products in high yields. The catalyst is reusable; however, there was reduction in the yield of the product. (C) 2008 Elsevier Ltd. All rights reserved.

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