期刊
TETRAHEDRON LETTERS
卷 50, 期 43, 页码 5903-5905出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2009.08.004
关键词
Diethyltartrate; Johnson-Claisen rearrangement; Acute ischemic stroke therapeutic agent; Arundic acid
资金
- IRCC
- IIT-Bombay
- CSIR New Delhi
A diethyltartrate-based synthesis of both enantiomers of the acute ischemic stroke therapeutic agent, arundic acid is presented. Separable diastereomers were obtained through the Johnson-Claisen rearrangement of the chiral vicinal diol based on the diethyltartrate skeleton and were converted separately into the two enantiomers of arundic acid. (C) 2009 Elsevier Ltd. All rights reserved.
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